Psychedelics

Should Psychedelics Be Legalized And Are They Medicine?

The legalization process does not stop with marijuana. The pro-drug agenda is taking the next step to legalizing all drugs by asking Colorado voters to create another for-profit drug industry by increasing access to psychedelic drugs by creating state “Healing Centers” or places where the public can readily purchase them. This will add more confusion and complexity to the growing addiction, mental and physical illnesses, and the regulatory nightmare that has resulted from states legalizing cannabis for profit.


Should we be leery of being Leary? Concerns about psychedelic use by psychedelic researchers 2022, Nov 15


A Physician’s Attempt to Self-Medicate Bipolar Depression with N,N-Dimethyltryptamine (DMT)

https://pubmed.ncbi.nlm.nih.gov/28686543/


Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression

Nov 3, 2022

In the 25-mg group, the incidences of response and remission at 3 weeks, but not sustained response at 12 weeks, were generally supportive of the primary results. Adverse events occurred in 179 of 233 participants (77%) and included headache, nausea, and dizziness. Suicidal ideation or behavior or self-injury occurred in all dose groups.

CONCLUSIONS

In this phase 2 trial involving participants with treatment-resistant depression, psilocybin at a single dose of 25 mg, but not 10 mg, reduced depression scores significantly more than a 1-mg dose over a period of 3 weeks but was associated with adverse effects. Larger and longer trials, including comparison with existing treatments, are required to determine the efficacy and safety of psilocybin for this disorder. (Funded by COMPASS Pathfinder; EudraCT number, 2017-003288-36. opens in new tab; ClinicalTrials.gov number, NCT03775200. opens in new tab.)